The Adipex-P® PrescriptionPLUS Lifestyle Program (Always seek medical advice before beginning diet) Adipex-P PrescriptionPLUS Lifestyle Program is available through your physician. These booklets offer information on diet and exercise to assist in weight loss. It also contains information for physicians who need information on prescribing Adipex-P as part of a PrescriptionPLUS Lifestyle Program. Statistics have demonstrated that any endeavor when coupled with a comprehensive plan has a much greater chance of success*. The PrescriptionPLUS lifestyle Program is far more than a diet plan; it is filled with valuable information to aid your patients in making those important lifestyle changes that are crucial to their long term health. * Variability of Body Weight and health outcomes in the Framingham Population, Lissner, et al, New England Journal of Medicine, June 27, 1991 Adipex-P is contraindicated in arteriosclerosis, cardiovascular disease, and moderate to severe hypertension. Other contraindications or adverse events include central nervous system effects, gastrointestinal disturbances, hives, and changes in libido. Exercise caution when prescribing anti-obesity drugs for patients with mild hypertension. Adipex-P is indicated as a short-term monotherapy in combination with a long-term obesity treatment program. Primary pulmonary hypertension (PPH) and cardiac valvular disease have been reported in patients receiving a combination of phentermine and fenfluramine or dexfenfluramine. The possibility of an association between PPH and the use of phentermine alone cannot be ruled out.

Adipex-P
Generic Name: phentermine (FEN ter meen)
Brand Names: Adipex-P, Fastin, Ionamin, Obenix, Obephen, Oby-Cap, Oby-Trim, Panshape M, Phentercot, Phentride, Pro-Fast HS, Pro-Fast SA, Pro-Fast SR, Teramine, Zantryl

What is the most important information I should know about Adipex?
Feedback for Adipex
39 CommentsRate it!8.9Taking Adipex together with other diet medications such as fenfluramine (Phen-Fen) or dexfenfluramine (Redux) can cause a rare fatal lung disorder called pulmonary hypertension. Do not take Adipex with any other diet medications without your doctors advice.

Adipex can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It can increase some of the side effects of Adipex. Adipex may be habit-forming and should be used only by the person it was prescribed for. Keep track of how many pills have been used from each new bottle of this medicine. Adipex is a drug of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.
You may have withdrawal symptoms, such as depression and extreme tiredness, when you stop using Adipex after using it over a long period of time. Do not stop using Adipex suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely.

What is Adipex?
Adipex is a stimulant that is similar to an amphetamine. Adipex is an appetite suppressant that affects the central nervous system.

Adipex is used togther with diet and exercise to treat obesity (overweight) in people with risk factors such as high blood pressure, high cholesterol, or diabetes.

Adipex may also be used for purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before taking Adipex?
Do not take Adipex if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take Adipex before the MAO inhibitor has cleared from your body.
Taking Adipex together with other diet medications such as fenfluramine (Phen-Fen) or dexfenfluramine (Redux) can cause a rare fatal lung disorder called pulmonary hypertension. Do not take Adipex with any other diet medications without your doctors advice.

Do not take this medication if you are allergic to Adipex or other stimulants, or if you have:
heart disease or high blood pressure;

arteriosclerosis (hardening of the arteries);

an overactive thyroid;

glaucoma;

if you are in an agitated state; or

if you have a history of drug or alcohol abuse.

Before taking Adipex, tell your doctor if you are allergic to any drugs, or if you have:

problems with your thyroid,

an anxiety disorder,

epilepsy or another seizure disorder, or

diabetes.

If you have any of these conditions, you may not be able to use Adipex, or you may need a dosage adjustment or special tests during treatment.

It is not known whether Adipex will harm an unborn baby. Do not take Adipex without first talking to your doctor if you are pregnant. It is also not known whether Adipex passes into breast milk or if it could harm a nursing baby. Do not take Adipex without first talking to your doctor if you are breast-feeding a baby. Do not give this medication to anyone younger than 16 years old without the advice of a doctor.
How should I take Adipex?
Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Taking high doses of Adipex over long periods of time can cause severe skin problems, sleep problems (insomnia), personality changes, and feeling hyperactive or irritable. Take this medicine with a full glass of water. It is best to take Adipex on an empty stomach before breakfast, or at least 10 to 14 hours before bedtime.
Adipex should be taken only for a short time, such as a few weeks.

Do not crush, chew, break, or open an extended-release capsule. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking or opening the pill would cause too much of the drug to be released at one time.
You may have withdrawal symptoms when you stop using Adipex after using it over a long period of time. Do not stop using this medication suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely.

Do not take Adipex in the evening because it may cause sleep problems (insomnia).

Stop taking Adipex if you have increased hunger or if you otherwise think the medication is not working properly. Do not take more Adipex for an increased effect. Taking too much of this medication can cause serious, life-threatening side effects.

Adipex may be habit-forming and should be used only by the person it was prescribed for. Keep track of how many pills have been used from each new bottle of this medicine. Adipex is a drug of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription. Store Adipex at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medication. An overdose of Adipex can be fatal.
Symptoms of a Adipex overdose may include confusion, hallucinations, feeling restless or aggressive, nausea, vomiting, diarrhea, stomach pain, irregular heartbeat, tremors, rapid breathing, confusion, hallucinations, feeling light-headed, fainting, or seizure (convulsions).

What should I avoid while taking Adipex?
Avoid drinking alcohol. It can increase some of the side effects of Adipex. Adipex can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
What are the possible side effects of Adipex?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Adipex and call your doctor at once if you have any of these serious side effects:
chest pain, swelling in your ankles or feet, feeling light-headed, fainting, or feeling short of breath, even with mild exertion;

fast or uneven heartbeat;

unusual thoughts or behavior, feeling restless or confused; or

increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure).

Less serious side effects may be more likely to occur, such as:

feeling nervous or anxious;

headache, dizziness, tremors;

trouble sleeping (insomnia);

dry mouth or an unpleasant taste in your mouth;

diarrhea or constipation; or

itching.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Adipex?
Before taking Adipex, tell your doctor if you are using any of the following drugs:

medicines to treat high blood pressure;

insulin or diabetes medication you take by mouth;

guanadrel (Hylorel), guanethidine (Ismelin);

antidepressants such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), or sertraline (Zoloft); or

antidepressants such as amitriptyline (Elavil, Etrafon), amoxapine (Ascendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), imipramine (Janimine, Tofranil), nortriptyline (Pamelor), protriptyline (Vivactil), or trimipramine (Surmontil).

If you are using any of these drugs, you may not be able to use Adipex, or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can affect Adipex. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?
Your pharmacist has information about Adipex written for health professionals that you may read.
What does my medication look like?
Phentermine is available with a prescription under the brand names Adipex and Fastin. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

Adipex-P 37.5 mg white, oblong, scored tablets with blue speckles

Adipex-P 37.5 mg light-blue-and-white capsules with two blue bands

Fastin 30 mg blue-and-clear capsules with blue and white beads

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (’Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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Updated safety information for oral ED medications, including CIALIS
Sudden loss or decrease in hearing, sometimes with ringing in the ears and dizziness, has been reported in rare instances in men taking prescription ED tablets, including CIALIS. It is not possible to determine whether these events are related directly to the PDE5 inhibitors, to other diseases or medications, to other factors, or to a combination of factors. If you experience these symptoms, stop taking CIALIS and contact a doctor right away.

Important Safety Information for CIALIS® (tadalafil)
CIALIS is indicated for the treatment of erectile dysfunction.
CIALIS IS NOT FOR EVERYONE. Tell your doctor about your medical conditions and all medications, and ask if you’re healthy enough for sexual activity.
Don’t take CIALIS if you take nitrates, often prescribed for chest pain, as this may cause a sudden, unsafe drop in blood pressure.
Don’t drink alcohol in excess (to a level of intoxication) with CIALIS, as this may increase your chances of getting dizzy or lowering your blood pressure. CIALIS does not protect against sexually transmitted diseases, including HIV. The most common side effects with CIALIS were headache and upset stomach. Backache and muscle ache were also reported, sometimes with delayed onset.
As with any ED tablet, in the rare event of priapism (an erection lasting more than 4 hours), seek immediate medical help to avoid long-term injury.
In rare instances, men taking prescription ED tablets (including CIALIS) reported a sudden decrease or loss of vision. It’s not possible to determine if these events are related directly to the ED tablets or to other factors. If you have a sudden decrease or loss of vision, stop taking any ED tablet and call your doctor right away.
Sudden loss or decrease in hearing, sometimes with ringing in the ears and dizziness, has been reported in rare instances in men taking prescription ED tablets, including CIALIS. It is not possible to determine whether these events are related directly to the PDE5 inhibitors, to other diseases or medications, to other factors, or to a combination of factors. If you experience these symptoms, stop taking CIALIS and contact a doctor right away.
Individual results may vary. In clinical trials, CIALIS was shown to improve, up to 36 hours after dosing, the ability of men with ED to have a single successful intercourse attempt. CIALIS has not been studied for multiple sexual attempts per dose.
CIALIS is available by prescription only. For additional safety information, talk to your doctor about this medicine and see the full Patient Information.

The US and Russia got no closer to settling their public differences over US plans that Russia sees as a potential threat and a turf battle for influence in nations once under the Soviet thumb.

Russian Foreign Minister Sergey Lavrov said he will take a closer look at US proposals meant to allay Russian fears, but added that the best way to end the disagreement would be to scrap the plan for placing missile interceptors in Poland and a tracking radar in the Czech Republic.

“We’ve leaned very far forward in this in an effort to provide reassurance,” but the United States plans to go ahead, Defense Secretary Robert Gates said Tuesday following two days of talks with President Vladimir Putin and other Russian officials.

The Russians promised to look over written US offers of cooperation, a sign that perhaps they are resigned to eventually accepting the US plan.

“Since the US is going to carry this out, those proposals that we are expecting to receive on paper today seemed to us, as I said, important and useful for the minimization of our concerns,” Lavrov said.

During a brief greeting witnessed by reporters Monday, Putin did not mention US plans for the missile shield, a marked contrast from his vehement opposition when he met in October with Gates and Secretary of State Condoleezza Rice, who returned to explore whether US concessions have softened Putin’s stance.

“I would say they listened very carefully,” Gates told reporters Tuesday. “President Putin took extensive notes last night and there was a lot done during the day today. That said, the full range of what we are now prepared to offer to discuss with the Russians is really just now after the day’s talks being put down on paper.”

There is no deadline, but Gates said he expected an answer “reasonably quickly.”

Gates said the US side spelled out more clearly some details of the proposals it made in the fall, which the Russians initially agreed to study and later rejected as not addressing their main concerns.

On Monday, Gates gave as an example the US suggestion that Russia be allowed to monitor the activities in Poland and the Czech Republic. He said the Russians initially thought this meant they would be limited to monitoring through their diplomatic presence in the Polish and Czech capitals. Gates said that was clarified to mean the Russians would be permitted a physical - but likely not continuous - presence at the missile defense sites, and that the Russians appeared to regard this more favorably.

At first the Polish and Czech governments objected to having Russian monitors on their soil. News But Polish Prime Minister Donald Tusk said Tuesday that his government would be open to discussing an arrangement.

“From our side there is a readiness to talk seriously about what this monitoring - that would give our neighbors a sense of security - could look like,” said Tusk, who noted that he spoke to both Bush and Putin about the idea.

Gates has stressed that no arrangement for Russian monitoring would be agreed to unless it was accepted first by the Polish and Czech governments, whose history with the former Soviet Union makes this a touchy subject.

The Americans proposed the visit to give a formal framework to numerous issues from economics to foreign affairs where the United States and Russia have common or overlapping interests. Gates and Rice carried a proposed document that lays out areas of agreement reached under Putin and Bush, with an eye to the coming political transitions in both nations. Putin steps down as president in May, and Bush leaves office next January.

The document, which was not released, also lists the trouble spots, among them the independence of Kosovo, which the US supports over strong Russian objection, and the planned missile shield.

The US says the shield is protection against a theoretical future threat from Iran, which already has some missile capability, or from North Korea, which has tested long-range missiles but has agreed to give up nuclear weapons.

Rice made a point of scheduling one meeting that spotlighted a prime example of US-Russia tension - American disappointment over Putin’s consolidation of political and economic power in the Kremlin. She and Gates had breakfast with leaders outside government, including some who have been publicly critical of Putin.